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Viagra 50 mg sildenafil P 0.Although no appreciable pharmacokinetic interaction between sildenafil and warfarin was observed in patients with PAH receiving the drugs concomitantly, the incidence of epistaxis was higher 9% than in those receiving sildenafil alone 2% Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics with CYP2D6 inhibitors such as selective serotonin-reuptake inhibitorsSSRIs, or tricyclic antidepressants Concomitant administration of sildenafil 80 mg 3 times daily and epoprostenol resulted in a viagra 50 mg sildenafil decrease 28% in sildenafil exposure and an approximate 22% decrease in mean steady-state sildenafil concentrations; these reductions are not considered clinically important.

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